New York Knicks vs Chicago Bulls Odds, Spread, and Totals

The New York Knicks will play the first of their two straight matchups against the Chicago Bulls on Friday. While the Knicks are off to a decent 2-2 start, the Bulls, just as everyone predicted, have started the season with a perfect 4-0 mark. Wins against the Orlando Magic and the Detroit Pistons lend this upstart Chicago team some legitimacy, but a win over the Knicks would notify the NBA that the Bulls are to be taken seriously.

Injuries are a familiar sight for the Knicks, and the early going of this campaign has not given them any respite. The lineup has missed starting center Mitchell Robinson for all four games so far, and aside from him, there have been an assortment of minor maladies to the rest of the lineup. Mercifully, the Knicks seem to be on the mend, as Robinson will likely be the only player to miss this game. New York will look to find a rhythm behind star guard Jalen Brunson and Karl-Anthony Towns to give Chicago its first blemish of the young season.

When comparing Chicago's 2024-25 roster to this one, there really are not many big differences. Despite that, a team that barely made the play-in tournament has somehow rattled off four straight wins. Center Nikola Vucevic has been off to a scorching-hot start, averaging 18.3 points and 13.2 rebounds throughout the early going. Guard Josh Giddey has been effective as both a scorer and a distributor, and sophomore Matas Buzelis has picked up right where he left off at the end of last season, scoring and handling the ball well. 

Spread

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Totals

Note: The above data was collected on Oct. 31, 2025, and may have changed since writing.

New York Knicks

Chicago Bulls

It is not a total surprise to see the Knicks as significant favorites given the established talent levels of both teams, but even with that being said, having faith in New York to cover is a tough prospect. 

The Knicks have not been particularly good on the road, losing their only two games away from Madison Square Garden. It does not help that the Bulls have obviously been red-hot and that New York's obvious answer for Vucevic in Robinson will miss this game. Vucevic should light up the stat sheet once more, and either Giddey or Buzelis will take on the role of a secondary scorer quite well. Chicago might not continue its win streak, but the Bulls should find a way to cover in front of their home fans.