Diamondbacks vs Yankees Odds, Spreads, and Total

After a late-inning collapse and 7-5 defeat last night, the New York Yankees look to even the series against the Arizona Diamondbacks tonight at Yankee Stadium. First pitch is set for 7:05 p.m. ET.

The Yankees (3-1) held a 4-2 lead into the eighth inning on Tuesday, bolstered by home runs from Jasson Domínguez and Anthony Volpe. However, New York's bullpen stumbled and surrendered five runs, highlighted by a two-out grand slam from Eugenio Suárez off reliever Mark Leiter Jr. 

The Diamondbacks (3-2) capitalized on the opportunity, with Suárez's grand slam serving as the decisive blow. Corbin Carroll also contributed a solo home run earlier in the game. Four Arizona relievers combined to deliver 4 2/3 scoreless innings to seal the win before giving up a meaningless home run in the bottom of the ninth to Yankees DH Ben Rice.

Tonight's matchup will start with the Yankees sending out left-hander Carlos Rodón to make his season debut. Last year, he posted a 3.15 ERA with 200 strikeouts over 180 innings. The Diamondbacks will counter with right-hander Zac Gallen, who recorded similarly impressive stats in 2024: 3.32 ERA and 210 strikeouts over 190 innings.

Spread

Moneyline

Total

*The above data was collected on April 2, 2025, and may have changed since writing.

Diamondbacks

Yankees

"Our prediction for this Yankees vs. Diamondbacks matchup is to take the Yankees on the money line, with the payout sitting at +100. We have the Yankees taking this one by a score of 5-4. Looking at the starting pitchers, we actually have both Nestor Cortes and Zac Gallen finishing with the same amount of strikeouts, with both projected to finish with five. However, we have Gallen finishing with a higher ERA and giving up more hits. As for the Yankees lineup, they are actually projected to finish with more home runs than the Diamondbacks, with the Diamondbacks finishing with the second-fewest home runs on the day." — Joe Jensen, Predictem

"Zac Gallen's Opening Day start didn't go exceptionally well. He threw only four innings, and allowed four hits, four walks and four runs en route to a 10-6 loss. Gallen's fastball command and overall efficiency looked poor. ... Lefty Carlos Rodón was excellent in his Opening Day start. He struck out seven over 5.1 innings, allowing just one run on four hits. He pitched to a 3.96 ERA over 32 starts in 2024, while striking out 195 batters over just 175 innings." — Alex D'Agostino, Sports Illustrated

"Carroll hit his first home run for the D-backs this season in Game 1 against the Yankees. Betting sites seem to believe the Gallen-Rodón duel is a good bet for the D-backs, but it's impossible not to place this Yankees lineup as a betting favorite. The Yankees' "butt bats" continue to be talked about, but while the rest of the league responds to this strategy, the Yankees' home run streak to start 2025 only continues. Our prediction for Diamondbacks vs Yankees is: Yankees ML." — Carlos Zabala, Sporty Trader